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Actively dividing B cells aNSCs in our study were shown
2018-10-24
Actively dividing B1 purchase BLZ945 (aNSCs in our study) were shown to go through three rounds of divisions before differentiating into C cells (referred as TACs in our study) (Ponti et al., 2013). However, the mechanisms regulating their behavior both in vitro and in vivo are still not known. Our
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In in vivo animal models
2018-10-24
In in vivo animal models, we observed no rejection signs in the iPS-RPE allografts of MHC-matched monkeys (DrpZ1 and DrpZ17); for example, fundus photographs revealed no exudation, FA showed no vascular leakage of fluorescein, and OCT indicated there was no retinal edema around the transplanted RPE
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br Experimental Procedures br Author Contributions br
2018-10-24
Experimental Procedures Author Contributions Acknowledgments This work is supported by national Portuguese funding through FCT, Fundação para a Ciência e a Tecnologia, project UID/BIM/04773/2013 CBMR, projects PEst-OE/EQB/LA0023/2013 and PTDC/SAU-ENB/111702/2009 to J.B., U01HL100408, NIH/N
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pteryxin cost br Experimental Procedures br Author Contribut
2018-10-24
Experimental Procedures Author Contributions Acknowledgments We wish to thank the cytometer unit of CABIMER for technical support, Diana Aguilar for critical reading of the manuscript, and Veronica Raker for style corrections. This work was funded by an R + D + I grant from the Spanish Mini
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Although previous studies have demonstrated the ability of r
2018-10-24
Although previous studies have demonstrated the ability of research-grade HuCNS-SC lines to differentiate in both immune-suppressed and immune-deficient models (Cummings et al., 2005; Sontag et al., 2014; Ager et al., 2015), we observed no terminal differentiation in the current study. In our prior
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Dedifferentiation has been considered as
2018-10-24
Dedifferentiation has been considered as one of the mechanisms rerouting cell fate by reverting differentiated cells to an earlier, more primitive phenotype. Interestingly, previous studies from both our group and others have demonstrated that dedifferentiation is a prerequisite for bone marrow stro
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The electrical properties of cells were
2018-10-24
The electrical properties of pi3k activation were recently analyzed by EIS during the differentiation of stem cells (Angstmann et al., 2011; Bagnaninchi and Drummond, 2011; Venkatanarayanan et al., 2013). These pioneering works have demonstrated a possibility of using changes in impedance as a bioma
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We speculated that MEKi might decrease DNA methylation
2018-10-24
We speculated that MEKi might decrease DNA methylation levels through the downregulation of the DNMT3 family. MEKi significantly diminished global DNA methylation levels and, surprisingly, was sufficient to induce high 5hmC levels. Because the TET family of dioxygenases that catalyze the conversion
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The presented hMOs have a great
2018-10-24
The presented hMOs have a great potential to be used for in vitro modeling of diseases that strongly affect the human midbrain, particularly PD (Michel et al., 2016). Patient-specific hMOs might reveal specific phenotypes that are not abundant in 2D cultures and therefore may be used for mechanistic
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br The technique of processing the time
2018-10-24
The technique of processing the time series of solar flare HXR The technique of processing the experimental data obtained using the BATSE spectrometer for simple single-pulse events is described in Ref. [3]. In essence, the technique entails constructing a mutual correlation function (MCF) for al
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br The technique of processing the time
2018-10-24
The technique of processing the time series of solar flare HXR The technique of processing the experimental data obtained using the BATSE spectrometer for simple single-pulse events is described in Ref. [3]. In essence, the technique entails constructing a mutual correlation function (MCF) for al
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br The configuration of the system for
2018-10-24
The configuration of the system for photochemical reaction imaging The system is placed in a compact case that is effectively an intraoral camera with a built-in emitter. The camera field of view at a working distance from the object (about 15 mm) is 1 cm2. The construction of the system provides
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The DCM assumes that the frequency dependence for
2018-10-24
The DCM assumes that the frequency dependence for the dielectric permittivity can be expressed as Expression (6) describes the dielectric function of a single-mode crystal in the phonon frequency range [13]. Here ωLO and ωTO are the frequencies of the longitudinal and the transverse optical phono
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Thin vertical lines in Fig show the calculated ranges of
2018-10-24
Thin vertical lines in Fig. 5 show the calculated ranges of focusing corresponding to three accepted restrictions: 2ΔαE-64 cost flows at the lens exit. One of the possible regimes of this sort has also been calculated. In this version, the first focusing electrode is electrically connected with the
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The fact that social capital was higher among not
2018-10-24
The fact that social capital was higher among not only dog owners may have a number of alternative explanations that merit further exploration. One AKT inhibitor VIII is that pets (of any kind) may be linked to perceptions of trust, a central tenant of social capital. Some observational studies hav
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