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br Conclusion br Competing interests br
2024-01-11
Conclusion Competing interests Funding The Bolger Prostate Cancer Research Fund (no grant number), the National Institute of General Medical Sciences of the National Institutes of Health (1-R01-GM58553, G. B. Bolger, principal investigator), and the National Cancer Institute of the NIH to t
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br Diabetic retinopathy Diabetic retinopathy is a severe sig
2024-01-11
Diabetic retinopathy Diabetic retinopathy is a severe sight-threatening complication associated with diabetes mellitus. It is one of the most common causes of preventable blindness in the world. The risk of developing microvascular diabetic complications increases in diabetic patients with an inc
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Neural activity resulting from sensory experience is require
2024-01-11
Neural activity resulting from sensory experience is required for the refinement and maturation of neural circuits during cortical critical periods. This refinement is thought to be important for functional optimization of primary sensory cortices, enabling critical functions such as feature detecti
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LOXs and CYPs are a series of iron
2024-01-11
LOXs and CYPs are a series of iron-containing enzymes that metabolize arachidonic AGN 194310 to form biologically active products, such as epoxyeicosatrienoic acids (EETs) hydroperoxyeicosatetraenoic acids (HETEs), prostaglandins, leukotrienes and thromboxanes [6]. Among these mediators, 12/15LOX ha
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While the mechanisms by which ALDH regulates cardiac
2024-01-11
While the mechanisms by which ALDH2 regulates cardiac responses to pathological stress remain unclear, the capillary rarefaction found in pressure-overloaded ALDH2 Tg hearts provides potential clues. Loss of capillary density and diminished endothelial function occur in pathological hypertrophy [46]
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br Introduction Alcohol i e ethanol is
2024-01-11
Introduction Alcohol, i.e., ethanol, is absorbed into the blood from the stomach to the small intestine, then distributed throughout the body. The metabolism of alcohol converting to acetic PFI-2 basically involves two enzymes; alcohol dehydrogenase converting ethanol to acetaldehyde and aldehyd
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Tissue distribution showed that ctrp was abundantly expresse
2024-01-11
Tissue distribution showed that ctrp9 was abundantly expressed in the kidney of male and female tilapia. In mice, the Ctrp9 was identified in adipose tissue, and the expression levels were higher in females than that of males (Wong et al., 2009). Recent studies indicated that Ctrp9 was also expresse
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Moreover an increase of extracellular calcium stimulates BMP
2024-01-11
Moreover, an increase of extracellular calcium stimulates BMP-2 expression of pulp Nocodazole via L-type calcium channel and ERK signaling, which can be attenuated by PD98059 and nifedipine . Dental pulp cells expressed little calcium-sensing receptors . immunohistochemistry staining also shows the
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By applying each external load to the G actin
2024-01-11
By applying each external load to the G-actin molecule, and measuring the elongation of the molecule, we computed force-displacement curves. The force versus displacement curve can be used to evaluate the tensile stiffness of the G-actin from a linear regression analysis. Followed by statistical ana
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PL for actin in vitro showed that its profiles
2024-01-11
PL for 78 9 in vitro showed that its profiles, including particular peak and intensity, could determine the length and thickness of an actin filament. Furthermore, we investigated if the PL intensity peak at approximately 340 nm can also be originated from another cytoskeleton filament, such as mic
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RN486 Regarding androgens it is known that they are also ess
2024-01-10
Regarding androgens, it is known that they are also essential for reproductive success (Walters et al., 2010). At the molecular level, their effects are produced mainly by dihydrotestosterone (DHT), arising from the conversion of testosterone by the enzyme 3-oxo-5-alpha-steroid-4-dehydrogenase (enco
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Zanamivir The altered frequency of CD
2024-01-10
The altered frequency of CD4+ T Zanamivir in 5-LO−/− mice led us to hypothesize that these leukocytes could be exerting a primary control of the inflammatory response. In fact, the lack of 5-LO resulted in the accumulation of CD4+CD25+ cells expressing Treg markers. It is plausible to speculate tha
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It is important to note that stable
2024-01-10
It is important to note that stable amnesia is, apparently, a general biological phenomenon and can be found in different animal species. In studies on rats, it was found that if reconsolidation of conditioned olfactory aversion memory was impaired by the antagonist of NMDA glutamate receptors, amne
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br Conclusions br Conflicts of interest br Acknowledgements
2024-01-10
Conclusions Conflicts of interest Acknowledgements This work was supported by Ege University Research Fund [BAP, 14-ECZ-030, 2016]. Introduction The interest in the effects of endocrine disrupting chemicals (EDCs) in the aquatic environment continues to increase over the past decade, sp
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Our outcrossing data confirmed that ACL and ACL have importa
2024-01-10
Our outcrossing data confirmed that ACL1 and ACL2 have important temporal and spatial functions in ascospore delimitation in G. zeae. When each ACL deletion mutant was used as male for outcrossing, nuclear division and spore delimitation were not properly progressed in most asci. Ascospores that con
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