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br Technical Note Fungal spoilage
2023-10-09

Technical Note Fungal spoilage of dairy products remains a major concern for dairy manufacturers despite the use of preventive and control approaches, including the use of chemical preservatives. Among methods that are increasingly used by industries for microbial contaminant control, biopreserva
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Hydroxysafflor yellow A br Polymorphic variation ERAP is pol
2023-10-09

Polymorphic variation ERAP1 is polymorphic and several single nucleotide polymorphisms (SNPs) in its gene that encode amino Hydroxysafflor yellow A changes have been associated with predisposition to a variety of diseases, ranging from viral infections to cancer and autoimmunity (Alvarez-Navarro
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As we previously observed in the
2023-10-08

As we previously observed in the NSFT (Fukumoto et al., 2014), the effect of LY341495 in the FST was also inhibited by a 5-HT1A receptor antagonist, indicating the role of the 5-HT1A receptor in the actions of LY341495. Among the 5-HT1A receptors, which exist both presynaptically and postsynapticall
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Glucose permeability studies demonstrated a high glucose flu
2023-10-08

Glucose permeability studies demonstrated a high glucose flux through the SF films used in the present work. Recent diffusion studies, including small molecular drugs and oxygen permeation through SF membranes [32], further support the quality of SF and its possible application as a material for bio
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br Dihydrotestosterone in adult fish and frogs br New
2023-10-08

Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance
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Recent studies demonstrated FoxO a enhances the protective f
2023-10-08

Recent studies demonstrated FoxO3a enhances the protective functions of autophagy in response to environmental stress , . FoxO3a coordinately activates autophagy by binding directly to the promoters of autophagy-related genes, including LC3, Gabarapl1, Beclin1, and Atg12 in atrophied skeletal muscle
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In addition to drawing attention to
2023-10-08

In addition to drawing attention to Ser454 of ACL as a phosphosite that is regulated by both BDK and PPM1K, our phospho-proteomics screen identified several additional sites in other proteins. For example, Ser25, Ser29, and Ser79 of the lipogenic enzyme acetyl-coA carboxylase 1 (ACC1) were found to
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In response to DSB the lesion recognition factor Mre Rad
2023-10-08

In response to DSB, the lesion recognition factor Mre11-Rad50-Nbs1 (MRN) complex helps the recruitment of ATM to the damage site and its activation by phosphorylation [29]. However, whether UV-damage recognition factors directly influence ATR and ATM recruitment and their phosphorylation is not clea
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Inflammations lead to the perturbation
2023-10-08

Inflammations lead to the perturbation of aromatase enzyme [112], which normally is responsible for a broad array of critical functions. Chemotherapy targets this enzyme, so this treatment option is never side-effect-free and not fully-effective. Therefore, the mankind should be careful so as not to
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Using the same techniques we found
2023-10-08

Using the same techniques, we found that UCP3 also has a half-life of between 1 and 4h [117]. In ap-1 transcription factor to UCP2 and UCP3, UCP1 and ANT had much longer half-lives and could not be degraded in the cell-free reconstituted system, suggesting their degradation is not mediated by the c
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br Author Contributions br Acknowledgments br Introduction C
2023-10-08

Author Contributions Acknowledgments Introduction Cerebral ischemia-reperfusion (I/R) injury is a pathological phenomenon that occurs after restoration of blood supply to Sumatriptan tissues subsequent to ischemia or hypoxia (Carden and Granger, 2000). It typically occurs after therapeutic
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Bioinformatics tools are becoming more powerful
2023-10-08

Bioinformatics tools are becoming more powerful and reliable due to the growing number and availability of experimentally determined protein structures (Arnold et al., 2006, Suplatov et al., 2015, Wiltgen and Tilz, 2009). The SWISS-MODEL and MODELLER programs are most frequently used for homology or
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br Experimental section br Abbreviations PSA
2023-10-08

Experimental section Abbreviations PSA, puromycin–sensitive aminopeptidase; APN, aminopeptidase N; AML, acute myeloid Leukemia; ALL, acute lymphoblastic leukemia; AADR, amino SIN-1 chloride deprivation response; PAN, puromycin aminonucleoside; DCC, dicyclohexyl carbodiimide; NHS, N–hydroxy suc
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The preferential expression of ALOX B
2023-10-08

The preferential expression of ALOX15B in human macrophages may explain why human genetic studies investigating the association of ALOX15 with cardiovascular disease did not show consistent results. Two rare functional polymorphisms have been characterized in the ALOX15 gene, which leads to increase
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br cDNA cloning gene structure and
2023-10-08

cDNA cloning, gene structure and chromosomal localization The cDNA for the leukocyte-type 12S-lipoxygenase was first cloned from porcine leukocytes [9], and later from mouse [10], [11], rat [12], [13], bovine [14] and rabbit [15] sources. The cDNA for the platelet-type 12S-lipoxygenase cDNA has b
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