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Ketogenic diets are more effective in promoting weight loss
2024-06-25
Ketogenic diets are more effective in promoting weight loss than conventional caloric restriction [26] however, their effect on hepatic glucose and lipid metabolism remains inconclusive. Blood glucose homeostasis is tightly regulated. In both mice and humans consuming KD, baseline blood glucose decr
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Epithelial mesenchymal transition EMT is the process by whic
2024-06-25
Epithelial-mesenchymal transition (EMT) is the process by which epithelial cells are trans-differentiated into motile mesenchymal cells. During EMT, epithelial cells reorganize their cortical bms webpage cytoskeleton, lose their junctions and apical-basal polarity, change cell shape, and reprogram
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Materials and methods br Results br Discussion The BV
2024-06-25
Materials and methods Results Discussion The BV-tag-based electrochemiluminescence immunoassay is an extremely sensitive assay. It has been employed for detecting analytes present in only picogram quantities (e.g., bacterial toxins [26], Bufexamac [19]), measuring the activity of basic carbo
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Although our data show that agrin accelerates
2024-06-25
Although our data show that agrin accelerates the innervation of engineered muscle tissue following implantation, there are still several issues that need to be considered. First, the use of primary muscle stem or progenitor PPACK Dihydrochloride synthesis (satellite cells) instead of an immortalize
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The first result of this paper is
2024-06-25
The first result of this paper is parallel to the positivity result given in [16]: Here the definition of approximate ACHE metric is the same as in [18]. See Definition 1 for details. The second result of this paper is parallel to the dna ligase extension formulae given in [2]. In particular, whil
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br Acknowledgements DHA was funded by a research grant from
2024-06-25
Acknowledgements DHA was funded by a research grant from Viamet and IMB and DHA were/are consultants for Viamet/Innocrin. DHA also supported by NIH P51-OD011106. Introduction Congenital adrenal hyperplasia resulting from 17alpha-hydroxylase and 17,20-lyase deficiency (17OHD) is a rare autosom
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For both the hydroxylation and lyase reactions the heme iron
2024-06-25
For both, the 17α-hydroxylation and 17, 20-lyase reactions, the heme iron center of P450 17A1 receives electron reducing equivalents from CPR. Both reactions require one pair of electrons and molecular oxygen for the conversion of the substrate into product in each catalytic cycle. However, the 17,2
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The link between HPV infection and
2024-06-25
The link between HPV infection and neoplasia has been well established. HPV encodes two oncogenes (E6 and E7) that drive bms-690514 progression by controlling the functions of tumor suppressor proteins p53 and Rb [7]. HPV is associated with more than 99% of cervical CESC cases [8]. CESC remains a m
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Aromatization of the pyrrole ring after anion capturing usin
2024-06-25
Aromatization of the pyrrole ring after anion capturing, using acceptor atoms with electron deficiency (B & Be), and substitution of strong electron withdrawing groups such as CN were three strategies used to design a new class of anion receptors. Comparison of the anion affinities of these anion re
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Thus phosphorylation of p was used to measure the
2024-06-25
Thus, phosphorylation of p38 was used to measure the intracellular potency of ASK1 inhibitors. In this assay, HEK293/AP-1luc Concanamycin A expressing human full-length ASK1 were incubated with compound for 18 h and then lysed and the level of phospho-p38 was quantified using the HTRF assay [33].
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As the experimental procedure used could reflect agonist
2024-06-24
As the experimental procedure used could reflect agonist-stimulation of both anterograde and retrograde APJ trafficking, as has been described for the δ-opioid peptide receptor (Zhang et al., 2006b, Zhang et al., 2006a), receptor internalization was more directly monitored by loading cell surface HA
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br Materials and methods br
2024-06-24
Materials and methods Results and discussion Conclusion The preparation of acrylic nanoparticles as aminosugar carriers could not be achieved by direct functionalization of poly(t-butyl acrylate) particles with saccharide groups. A four-step procedure starting from a protected derivative of
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Angiogenesis is a process of formation of
2024-06-24
Angiogenesis is a process of formation of new vessels from arterial vascularization created by endothelial cells. It is essential for the continuous growth of the tumor because it supplies the tumor with nutrients and oxygen, and eliminates cellular waste, which can be toxic to cancer cells [8]. Inf
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Some of previous immunohistochemical studies have compared t
2024-06-24
Some of previous immunohistochemical studies have compared the levels of AR expression in low-grade versus high-grade and/or non-muscle-invasive versus muscle-invasive tumors. There was a significant or marginal decrease (Boorjian et al., 2004, Miyamoto et al., 2012b, Rau et al., 2011, Shyr et al.,
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br Experimental section br Introduction Microglia
2024-06-24
Experimental section Introduction Microglia were discovered as a novel cell population in e 64 in 1933 by a Spanish physician and histologist Pío del Río-Hortega [1]. In the eye, scientists used Hortega's staining technique to label the microglia in the retinal outer plexiform layer (OPL) in
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