• br Conflict of interest br Acknowledgement br

  2018-11-06

  

  Conflict of interest Acknowledgement Introduction Chicken meat is favoured by consumers around the world because of its desirable nutritional qualities, such as a low fat content and a relatively high concentration of polyunsaturated fatty acids [1]. Fresh meat products are usually marketed

• However free radicals have also been

  2018-11-06

  

  However, free radicals have also been suggested to cause DM [11]. Although free radicals typically originate from the surrounding environment, several physiological and biochemical processes in the human body also produce reactive oxygen species, such as the superoxide radical, hydroxyl radicals, a

• br Acknowledgments This study was funded by a

  2018-11-06

  

  Acknowledgments This study was funded by a grant provided by the Royan Institute. We thank Mr. Ehsan Janzamin for his unlimited assistance in the Flow Cytometry Laboratory, Dr. Abass Piryaei and Leila Sattarian in the Histology Laboratory, Mr. Chehrazi for statistical analysis, and Miss Saloomeh

• To study this complex neuroprotective pathway a common

  2018-11-06

  

  To study this complex neuroprotective pathway, a common endpoint needs to be identified. A potential pathway involves the regulation of the major cellular antioxidant glutathione. Glutathione biosynthesis, which begins with the import of cystine dimers through the cystine glutamate exchanger (System

• Although colorectal CSCs Co CSCs were originally

  2018-11-06

  

  Although, colorectal CSCs (Co-CSCs) were originally identified as a small group of CD133+ BV6 present in the primary tumors which exhibited high tumorigenicity in immunodeficient mice (O\'Brien et al., 2007; Ricci-Vitiani et al., 2007), some studies have shown that CD44+ colorectal cancer cells als

• Although adult CMs have very limited proliferative

  2018-11-06

  

  Although adult CMs have very limited proliferative capacity, it has been suggested that a small population of these cells in regions adjacent to a myocardial infarct, retain the ability to divide (Kajstura et al., 1998; Beltrami et al., 2001). Thus, enhancing their proliferation may augment repair i

• In our previous study we reported a genetic diagnosis

  2018-11-06

  

  In our previous study, we reported a genetic diagnosis of a GT patient with two different mutations in the two ITGA2B alleles. Both mutations activated a same recessive intron splicing site and cause a 99-base deletion in IIb mRNA (Li et al., 2011). In the current study, we successfully established

• Host pathogen interaction is a balancing

  2018-11-06

  

  Host-pathogen interaction is a balancing act as viruses evolved to have strategies to evade the host defense system. HCV NS3, core and NS5A proteins are involved in immune evasion by modulating specific and innate immune pathways (Basu et al., 2001; Horner and Gale, 2013). NS3 protease can effective

• Our coculture experiments demonstrated that all

  2018-11-06

  

  Our coculture experiments demonstrated that all three MSCs showed a similar low in vitro proliferation; for most patients coculture of all three MSCs with primary human AML DMXAA did not alter MSC proliferation but a minor increase in the proliferation was seen for a minority of patients. No or onl

• The last aspect we want to address in this review

  2018-11-06

  

  The last aspect we want to address in this review is the importance of suitable cell culture conditions for targeting and single cell cloning of human PSCs. This is probably the most challenging aspect since there are significant variances between different human PSC clones concerning proliferation,

• Despite these achievements in iNSC technology little

  2018-11-06

  

  Despite these achievements in iNSC technology, little is known on how cellular identities of iNSCs differ from those of NSCs in comparison to pluripotent stem cell-derived NPCs. For instance, it is currently unknown to what extent neural, metabolic and stress response pathways differ between these n

• br Materials and methods br Acknowledgments

  2018-11-06

  

  Materials and methods Acknowledgments We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids for reprogramming. We thank Bente Smith Thorup for excellent technical assistance in the cell culture. We thank Mehri Mirrajei for cytogenetic technical assistanc

• The SWI SNF complex consists of

  2018-11-06

  

  The SWI/SNF complex consists of 15 core subunits whose unique composition is critical for its distinct functions in different types of cells (Kadoch et al., 2013; Wu et al., 2009). In our study, we demonstrated that both BAF170 and BAF155 existed in the human BRG1-SWI/SNF complex and were enriched

• The DNA damage repair system involves a complex

  2018-11-05

  

  The DNA damage repair system involves a complex network in which miRNAs play important roles (Chen and Rajewsky, 2007; Song et al., 2011; Wan et al., 2011). For example, miR-24 and miR-138 can downregulate H2AX, leading to high sensitivity to radiation and weak repair capacity (Lal et al., 2009). mi

• One therapeutic approach for SCI is

  2018-11-05

  

  One therapeutic approach for SCI is cell transplantation. For this Torin1 approach, cell survival is also a critical variable for preclinical models. The advantages of constitutively immunodeficient mice versus immunosuppression in immunocompetent mice in achieving maximal donor cell engraftment for

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