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Influenza proteins inside the viral envelope are highly
2018-10-23
Influenza proteins inside the viral envelope are highly conserved across different strains and subtypes of influenza. Two internal proteins that have been extensively studied in the context of influenza infection are nucleoprotein (NP) and matrix protein 1 (M1). NP binds and transports the RNA genom
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The strong negative association between IgG and IgM levels
2018-10-23
The strong negative association between IgG and IgM levels and CHD events needs to be considered in the context of other biomarkers that have been evaluated as adjuncts to traditional risk assessments. Although the ASCOT-CRP substudy concluded that measuring CRP had little utility in refining CV ris
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Of note it is not known whether the
2018-10-23
Of note, it is not known whether the findings observed in the HOD model will translate to murine RBCs expressing other antigens, or to humans. Human studies investigating the role of RBC storage duration on alloimmunization and other adverse effects have reported varied outcomes (Dinardo et al., 201
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The following are the supplementary data related
2018-10-23
The following are the supplementary data related to this article. Author Contribution Acknowledgments This study is supported in part by the Bureau of Health Promotion, Department of Health, R.O.C. (Taiwan) (DOH99-HP-1205), Taiwan Ministry of Health and Welfare Clinical Trial and Research Cen
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A technique recently developed for in
2018-10-23
A technique recently developed for in vitro amplification of prions, the RT-QuIC (quaking-induced conversion) assay, is a highly sensitive and specific technique that can detect small amounts of prion-seeding activity (Takatsuki et al., 2015). In our study, the detection limit of the RT-QuIC assay w
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br Methods br Results Overall each participant performed
2018-10-23
Methods Results Overall, each participant performed 20 headers, achieving a mean force of impact of 13.1±1.9g (Table 1), with a coefficient of variance of 18%(±3%). Discussion Following a standardized session of football heading designed to simulate routine soccer practice our data demonst
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The role of MeCP in malignancy has not been extensively
2018-10-23
The role of MeCP2 in malignancy has not been extensively researched. Emerging evidence suggests MeCP2 as a key oncogene in cancer development. It was reported a higher level of MeCP2 expression in neoplastic breast tissues than in non-neoplastic tissues (Müller et al., 2003). We previously reported
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Here we show that the genetic disruption of
2018-10-23
Here, we show that the genetic disruption of the regulatory system maintaining systemic iron homeostasis causes age-dependent and genotype-specific pulmonary iron accumulation, increased lipid peroxidation, and gene responses consistent with pulmonary iron overload and oxidative stress; TfR1 and DMT
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Our results agree with the strategy of
2018-10-23
Our results agree with the strategy of shortening the duration of dual NS5B/NS5A combined therapy to 8weeks, but based on an on-treatment response predictor rather than a baseline variable. This supports the findings of many other studies for the validity of early on-treatment response kinetics as a
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Zinc is an essential nutrient for microbial
2018-10-23
Zinc is an essential nutrient for microbial growth, but can be toxic in excess (Blencowe and Morby, 2003; Coleman, 1998). The delicate balance between zinc sufficiency and toxicity is maintained by bacterial metal homeostasis systems (Klaus, 2005; Moore and Helmann, 2005). The GAS metalloregulator,
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br Search Strategy and Selection Criteria br
2018-10-23
Search Strategy and Selection Criteria Conflicts of Interest Acknowledgments Introduction Chronological age is a major risk factor for functional impairments, chronic diseases and mortality. However, there is still great heterogeneity in the health outcomes of older individuals (Lowsky e
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Our data indicated that CRP may be associated
2018-10-23
Our data indicated that CRP may be associated with tissue lesions. In addition to hepatic synthesis (Pfafflin and Schleicher, 2009), CRP can be synthesized by lung crf1 (e.g. epithelial cells, lymphocytes) (Ramage et al., 2004; Marc et al., 2004). However, local production in extrahepatic synthesis
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The next question elicited information about
2018-10-23
The next question elicited information about stated preference recreation behavior with improved quality. Respondents were asked: “After enforcement of the tougher pollution control laws do you think that you would participate in any recreational activities on or near the (Albemarle and) Pamlico Sou
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br Microorganism cultivation and secretome extraction The fu
2018-10-23
Microorganism cultivation and secretome extraction The fungal isolates belonging to Aspergillus sp. isolated, identified and labeled as A. fumigatus LF9 was used in this study [3]. DNA sequence of this isolate is available in GenBank under accession no. JF815073. A. fumigatus LF9 was cultivated a
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However the use of friction surfacing process for many appli
2018-10-22
However, the use of friction surfacing process for many applications has been limited due to the difficulty of monitoring and control of the process outputs, such as bond quality and coating dimensions [4]. Proper selection of process parameters is vital for obtaining the quality coatings using fric
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