• The defining molecular feature of Ewing sarcoma is

  2020-11-06

  

  The defining molecular feature of Ewing sarcoma is the characteristic EWSR1/ETS fusion protein, most commonly involving EWSR1 and FLI1 (Delattre et al., 1992, May et al., 1993). EWS–FLI1 causes global changes in gene expression both by directly regulating gene expression and by causing changes in ch

• br Results br Discussion MSCs derived from

  2020-11-06

  

  Results Discussion MSCs derived from the bone marrow and adipose tissue have been shown to promote the growth and metastatic ability of breast cancer and other human malignancies, but the mechanisms are incompletely understood (Barcellos-Hoff et al., 2013, Cuiffo et al., 2014, Del Pozo Martin

• br Theory br Method To test our hypotheses as shown

  2020-11-05

  

  Theory Method To test our hypotheses as shown in Fig. 1, we conducted a survey at an international media company (hereafter referred to as ‘MediaCo’) headquartered in the UK. Its 5500 employees are dispersed throughout the world, partly due to massive acquisitions within the past decade. In ex

• Impulsive burying and freezing behaviors in

  2020-11-05

  

  Impulsive burying and freezing behaviors in response to aversive stimuli may represent attempts to avoid novel and/or aversive stimuli. These behaviors can be assessed utilizing the marble burying and conditioned fear tasks, respectively. For example, Wistar rats in proestrus and ovariectomized rats

• Although CCR expression clearly identifies MBC

  2020-11-05

  

  Although CCR6 expression clearly identifies MBC precursors within the GC, we found that the expression of this chemokine receptor by responding Thiorphan was not required for MBC differentiation and had no detectable impact on the GC subsets analyzed in this study. Although this is in agreement wit

• Immunofluorescence assays were performed to localize the

  2020-11-05

  

  Immunofluorescence assays were performed to localize the enzyme during growth and differentiation to further characterize Giardia E1. As stated before, the assays showed that the Kasugamycin hydrochloride mg generated recognized specific E1 forms (E1-114, E1-90 and E1-67 with anti-gNTE1; and E1-47 w

• Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) In the

  2020-11-05

  

  In the past few years we and others have reported that GLP-1 may also be secreted by sub-populations of alpha Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) in human pancreatic islets (Marchetti et al., 2012, Ellingsgaard et al., 2011), which could contribute to beta cell function and surviva

• br Acknowledgements The authors are supported

  2020-11-05

  

  Acknowledgements The authors are supported by National Institutes of Health grants (CA162804, CA92584, and CA13499 to DJC and CA166677 to BPPC) and Cancer Prevention and Research Institute of Texas (RP110465 to DJC). The cellular response to DNA double-strand break (DSB) formation is an essent

• Vincristine br Results and discussion To check the hypothesi

  2020-11-05

  

  Results and discussion To check the Vincristine that the charge of α-synuclein can be altered due to the glycation, we measured zeta potential of native α-synuclein and α-synuclein glycated by two different glycating agents, methylglyoxal (MG) and glyceraldehyde-3-phosphate (GA-3-P). The value f

• br DDR role in kidney Thirty eight papers

  2020-11-05

  

  DDR1 role in kidney Thirty-eight papers are reported in PubMed upon the keyword search “DDR1 AND kidney”. Careful examination of those papers shows that only 31 are related to DDR1\'s role in glomerulosclerosis and renal fibrosis, 24 of those being research and the rest review articles. Since the

• Based on the finding described above the present

  2020-11-05

  

  Based on the finding described above, the present study was designed to investigate the effects of specific CRF receptors, CRF1 and CRF2, in the BLA and CeA on the duration of TI in guinea pigs (Cavia porcellus). To this end, we evaluated whether administration of the CRF1 atp citrate lyase inhibito

• br Materials and methods br Results

  2020-11-05

  

  Materials and methods Results Discussion The main finding of the present study is that selective ETA and dual ETA/ETB receptor blockade markedly improve endothelium-dependent vasodilatation in patients with type 2 diabetes and vascular complications. The magnitude of improvement did not dif

• Here we examined whether Intracellular ER may mediate Cd ind

  2020-11-05

  

  Here, we examined whether Intracellular ER may mediate Cd-induced ovarian cancer proliferation. To determine this relationship, we used ICI 182,780 as a general inhibitor of ERα and ERβ. The results suggest a metalloestrogenic effect of Cd in ovarian cancer cell lines. Inconsistency with our results

• Since the interaction between the E and E is

  2020-11-04

  

  Since the interaction between the E2 and E3 is weak and transient, it has been difficult to identify novel interactions between specific E2/E3 complexes [59], [64]. Here we used a modified bait consisting of the Mulan RING domain fused to one of the four E2s isolated in our screen and expressed in y

• br Acknowledgements br This work was supported by grants fro

  2020-11-04

  

  Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Grant No.: 30260088) and the prophase research for National “973” Project of China (Grant No.: 2007CB116203). The DNA sequences of Hbvp1 and the Hbvp1 promoter were deposited in GenBank, an

15825 records 748/1055 page Previous Next First page 上5页 746747748749750 下5页 Last page